If anyone says I love God, but hates his brother, he is a liar.  For anyone who does not love his brother, who he has seen, cannot love God, whom he has not seen.  Whoever loves God must also love his brother.  

Share QuizNext Quiz Go to BabaMail Home Subscribe My Profile Topics English Personality Trivia Health Math IQ Spirituality Skill Edit Profile Help Contact us About Terms Of Service Privacy Policy Follow Us English Personality Trivia Health Math IQ Skill My Scores Quizzes > Personality Your Personality IQ! Natalie S. Share Join Us Many believe that the two most important measures that can be used to analyze people are learning capacity (IQ) and emotional intelligence (EQ). The first refers to a person’s ability to solve problems that require effective thinking and the other affects the ability to identify, evaluate and manage emotions. Although these are two different areas, it is impossible to separate them completely, and it is clear that our character has an impact on our type of intelligence and the main strengths of our IQ. To find out how your personality affects your intelligence just answer the following questions and choose to what extent you agree or disagree with the statements presented to you… You have interpersonal intelligence If you’ve always been told that you are a sociable and open person, it is because your personality and intelligence guide you to dealing with other people and help you create close, meaningful relationships with relative ease. To you, it probably doesn’t seem strange or special, but there are many good people who don’t have these important skills. Share your results with friends to learn more about them! Share Result   Share Quiz  WhatsApp   Next Quiz Found a mistake? Rate: You may also like: Recommended by Personality Where Are You On the Funny-Meter? 12 QsPersonality This Association Test May Surprise You… 12 QsSpirituality What Kindness Do You Carry in Your Heart? 10 QsPersonality What Kind of First Impression Do You Make? 12 QsPersonality Are You a Nice Person? 15 QsPersonality What Kind Of Heart Do You Have? 12 QsWho Am I How Does Your Brain Work? 10 QsSpirituality What’s Your Purpose? Take Our Quiz and Find Out! 10 Qs Personality Quizzes Your Personality IQ! 15 Qs This Photo Test Will check your Stress Level 10 Qs How Fast Do You Fall in Love? 12 Qs How Can You Make Money on the Side? 12 Qs Are You Predictable? 12 Qs Are You Burnt-Out, Stressed or is All Under Control? 12 Qs How Spontaneous are You? 11 Qs What’s Your Secret Agenda? 12 Qs Which Natural Phenomenon Represents You? 15 Qs What is Your Most Destructive Instinct? 13 Qs How Rigid is Your Thinking? 13 Qs What is the Spice of Your Life? 13 Qs Image Test: How Do You Think? 12 Qs Can This Coffee Test Reveal More About You? 10 Qs What Would You Do if You Ruled the World? 12 Qs Which Planet Matches Your Personality? 13 Qs Do You Lie a Lot? 12 Qs Who Would You Be in the FUTURE? 12 Qs What Kind of Garden Grows in Your Mind? 13 Qs Which Car Should You Optimally Drive? 12 Qs Your Sleep Habits May Reveal Your Future… 10 Qs Which Action Star Would You Be? 12 Qs Are You More Empathetic or Sympathetic? 12 Qs Are You in a Toxic Relationship? 10 Qs Which Personality Group Do You Belong In? 12 Qs What Does Your Routine Say About You? 10 Qs What is Your Perfect Adventure? 12 Qs What Kind of Assistant Do You Need? 12 Qs Globalist or Nationalist? 12 Qs What Reality Show Would You Be On? 11 Qs What Would You Be Famous For? 12 Qs Choose Colors to Find Your Soulmate 12 Qs Which Human Emotion Are You? 11 Qs How Afraid Are You of Dying? 12 Qs Are You Emotionally Strong? 11 Qs What Kind of Bliss Do You Experience? 11 Qs Sign Up for a Free Daily Quiz! Continue With: By continuing, you agree to our T&C and Privacy Policy English Quizzes English Quiz: Complete the Proverb! Will You Complete These English Proverbs? Personality Quizzes What You See in These Pictures Says a Lot About You… What Animal Do You Think Most Like? Trivia Quizzes Guess Which Country This Person is From Which Country is It? Health Quizzes See if You Have Photographic Memory! Which Number Do You See? Math Quizzes It’s All About the Fractions 12 Problems Await to Challenge You! IQ Quizzes Are You Logical Enough to Pass This Quiz? The 3-Part IQ Test Spirituality Quizzes Who Were Your Ancient Ancestors? What Kind Of Tree Is Hiding In Your Personality? Skill Quizzes Can You Speak All of the Languages of Love? Odd One Out: Colorful Foods Edition Contact us | Help | About us | Terms | Privacy policy | Categories | Popular Tags | Popular Searches | Archive | Collections

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For He repays man according to his work, and makes man to find a reward according to his way.  This means that God will find a way to make man repay according to Man’s work and ways.  This means retribution for man’s actions.  I remember when I had to repay my fines to the Dayton Ohio Montgomery County Court System on July 15th 1985 for stealing two pairs of sweatsuits from Rikes Department Store in Dayton, Ohio. The crime happened on Friday June 21, 1985.

Next, I went to jail and the judge ordered me to go to work and repay my fines.  I pleaded guilty for petty theft.  I knew that I was guilty of the crime.  God made sure that I will repay according to my works and ways.  I was a High School Senior when I got into trouble for dealing with the wrong people.

Finally, the moral of the story is you must reap what you had sown.  What comes around goes around.  This is in Job 34:11 and Galatians 6:7.  This is the truth.

WOW!! You totally aced it!! Share the word:)

You aced a spelling test that most Americans can barely pass. English is your first language, and you are definitely an incredibly perceptive person. People who scored as high as you did are most likely creative, stubborn, and quick to understand things. Are we spot-on? Let us know in a comment below, and share the quiz with the world!!

Good Morning Everyone!!  I want to inform all of you that I suffer from Type 2 Diabetes Full Blown.  Therefore, I am in the advance stages of my disease.  I know that this is my first time taking metformin 500mg medication.  I know that this is not very easy to talk about because I am having nerve pain right now.  My family members and friends had informed me that it would get worse for me.

I’m having skin problems as well as stress that is very high at the moment.  I want to say that my health insurance did not approve me for the medication metformin.  I already know the side affects of taking metformin in advance.  I am the only one in my family members that are taking medicine for diabetes.  Of I die from this dreadful disease it would be all my fault.

I am being very honest about having diabetes because my family members and friends want to know exactly how I feel each day of the week.  I am very scared to die from the disease.  My family members are much more healthier than me.  I am the type of person who deals with my problems with the assistance from God.  Yes I will admit that I am going to need help from other people.

I know that everything that I am going through is inside of the Holy Bible.  I can receive God’s Help for a cure of the disease.  I have been crying since last week.  I guess it is too late to display my emotions.  Everyone else warned me in advance about the disease.  I have to accept it like a real man.  It is too late to punk out about something that I became aware of years ago.  This is all my fault for not listening to the people who have informed me in advance.

Finally, I have to man up and act like a real man.  The medication metformin is going to make my stomach hurts very bad.  I already have stomach ulcers and acid reflux disease that I have had since 1996.  My brother performed my surgery in the past 27 years ago.  I guess I was not taking better care of myself back then.  This is a thorn that is inside of my flesh right now.  I also suffer from grandmal seizures as well.  I suffer from Schizoid Affective Disorder and Schizophrenia.  I have to be honest with everyone about having a terminal illness right now.  I might as well cry myself to sleep for the rest of my life right now.  Please keep me and my family members and friends in your prayers and thoughts.  This is something that I am going to deal with for the rest of my life.  I have Type 2 Diabetes Full Blown right now.  This means that I am in the advance stages of the disease.

I am a 58 year old man who has a lot of common sense.  I am highly educated and I have changed my overall behavior for the better.  I guess that God does not want me to cry anymore.  I have to deal with something that should have been prevented years ago.  Where do I go from here?  This is a question that I have to ask myself every single day of the week.  I have to eat just to stay alive right now.

I have to talk with my psychiatrist about my new health problems.  Please keep me in your prayers and thoughts because I am in need of prayers and nothing else.

You Passed!

You passed the ‘Knowledge of the Arts’ Exam, 99% of people fail. You must be a good learner who wonders about everything and never runs out of questions. You are a masterpiece!

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J Res Med Sci. 2014 Jul; 19(7): 658–664. 

PMCID: PMC4214027

PMID: 25364368

Metformin: Current knowledge

Hamid Nasri and Mahmoud Rafieian-Kopaei1

Author informationArticle notesCopyright and License informationPMC Disclaimer

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Abstract

Diabetes mellitus is a group of metabolic disorders in which the blood glucose is higher than normal levels, due to insufficiency of insulin release or improper response of cells to insulin, resulting in high blood pressure. The resultant hyperglycemia produces sever complications. Metformin drug has been shown to prevent diabetes in people who are at high risk and decrease most of the diabetic complications. Recent reports on metformin, not only indicate some implications such as renoprotective properties have been suggested for metformin, but some reports indicate its adverse effects as well that are negligible when its benefits are brought into account. We aimed here to review the new implications of metformin and discuss about the concerns in the use of metformin, referring to the recently published papers.

Keywords: Diabetes, diabetes mellitus, diabetic nephropathy, glucose, metformin, new applications, polycystic ovary syndrome, renoprotection

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INTRODUCTION

Diabetes mellitus is a group of metabolic disorders in which the blood glucose is higher than normal levels, due to insufficiency of insulin release or improper response of cells to insulin, resulting in high blood pressure. The resultant hyperglycemia produces the classical symptoms of polyuria, polydipsia and polyphagia. It may also cause nerve problems, kidney problems, and blindness, loss of limbs, and sexual dysfunction, increase in heart attack or stroke.[1] Metformin (a biguanide derivative), by controlling blood glucose level decreases these complications. Metformin works by helping to restore the body’s response to insulin. It decreases the amount of blood sugar that the liver produces and that the intestines or stomach absorb.[2] Metformin, other than hypoglycemic activity, has been taken with diet and exercise changes to prevent diabetes in people who are at high risk for becoming diabetic. It is also used in women with polycystic ovarian syndrome. Metformin may make menstrual cycles more regular and increase fertility.[3] Metformin was first synthesized and found to decrease the blood glucose level in the 1920s; however, it was not used for a long time. The use of metformin was rekindled in 1957, when the results of a clinical trial were published confirming its effect on diabetes. Metformin is now widely prescribed as an anti-diabetic drug; however, there have been serious concerns about its adverse effects, especially ketoacidosis.[4] Recently, not only some implications have been discovered for metformin, but also there are reports indicating that its adverse effects are negligible when its benefits are brought into account.[3] Theoretically, its use has been prohibited in a large group of patients with type 2 diabetes mellitus due to the risk of lactic acidosis. However, it has been shown that several diabetic patients who are considered to be at risk have received metformin with no increased risk of lactic acidosis.[2,3,4,5] Furthermore, recently some papers have been published indicating renoprotective properties for metformin. We aimed here to review the new implications of metformin and discuss about the concerns in the use of metformin, referring to the recently published papers.

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NEW AND OLD IMPLICATIONS AND THE MECHANISMS OF ACTION

Diabetes mellitus

Metformin is primarily used for the treatment of type 2 diabetes mellitus, particularly in obese.patients. Metformin has been shown to reduce diabetes mortality and complications by thirty percent compared to insulin, glibenclamide and chlorpropamide.[5]

Metformin reduces serum glucose level by several different mechanisms, notably through nonpancreatic mechanisms without increasing insulin secretion. It increases the effects of insulin; hence, it is termed “insulin sensitizer”. Metformin also suppresses the endogenous glucose production by the liver, which is mainly due to a reduction in the rate of gluconeogenesis and a small effect on glycogenolysis. Moreover, metformin activates the enzyme adenosine monophosphate kinase (AMPK) resulting in the inhibition of key enzymes involved in gluconeogenesis and glycogen synthesis in the liver while stimulating insulin signaling and glucose transport in muscles. AMPK regulates the cellular and organ metabolism and any decrease in hepatic energy, leads to the activation of AMPK. This study to an extent has put forth to explain the mechanism of metformin action on liver gluconeogenesis.[6,7]

Furthermore, metformin increases the peripheral glucose disposal that arises largely through increased non-oxidative glucose disposal into skeletal muscle. It usually does not cause hypoglycemia and this cause to be considered as a unique anti-diabetic drug.[8]

Treatment of diabetes with metformin is associated with less weight gain compared with insulin and sulfonylureas. Weight gain helps in better glucose control. In a study it was shown that, over a 10-year treatment period, the patients treated with metformin gained about one kg, the patients treated with glibenclamide gained about three kg, and the patients treated with the insulin gained six kg weight.[9]

Pre-diabetes

The chance of developing type 2 diabetes mellitus may decrease in people at risk for this disease; however, dieting and intensive physical exercise may work significantly better for this purpose. In a large study in the United States, participants were given placebo, lifestyle intervention or metformin, and followed for three years. The lifestyle modifications included a 16-lesson training on exercise and dieting followed by monthly sessions for individuals with the aim of decreasing the body weight by 7%. These patients under this group were engaged in a physical activity for about 150 minutes/week. The incidence of diabetes mellitus in this group was by 58%, and in metformin group by 31%. After ten years, the incidence of the disease was lower by 34% in the patients on diet and exercise and 18% in the metformin group.[10]

Gestational diabetes

Several trials have suggested that metformin is as safe and effective as insulin for the treatment of gestational diabetes,[11] and it has been suggested that the mothers who have used metformin instead of insulin might be healthier in the neonatal period.[12] However, evidence is still lacking on the long term safety of metformin for both children and mothers.[13]

Polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is frequently associated with resistance to insulin and since 1994, metformin has been proposed as a treatment for PCOS.[14] In 2004, National Institute for Health and Clinical Excellence recommended to prescribe metformin for women with PCOS and a body mass index above 25 for anovulation and infertility when other therapies have failed to produce acceptable results.[15] However, several subsequent reviews did not show promising results and did not recommend it further or at least as a first-line medication,[16] except for women with glucose intolerance.[17] The guidelines usually suggest clomiphene to be the first treatment and recommend lifestyle modification independent from drug therapy.

A systematic review using comparative trials of clomiphene and metformin found equal results for infertility[18] and A BMJ editorial suggested that metformin should be used as a second choice, if clomiphene treatment fails.[19] Furthermore, a large review using 27 clinical trials found that metformin was not associated with any increase in the number of live births; however, it improved ovulation rates, especially when it was used in combination with clomiphene.[20]

Further, a review recommended metformin as a first choice because of positive effects on insulin resistance, hirsutism, anovulation and obesity, which are often associated with polycystic ovary syndrome.[21]

The different trial designs might be the reasons for the contradictory results. For example, considering live birth rate instead of pregnancy as the endpoint might have biased a few trials against metformin.[22] Another explanation is that metformin may have different efficacy in different populations.

Cancer protection

A large case-control study has suggested that metformin might protect patients against pancreatic cancer. In this study, the risk of pancreatic cancer in metformin group was 62% lower than in placebo group who did not use metformin. The participants having sulfonylureas or insulin were found to have a 2.5-fold and 5-fold higher risk of pancreatic cancer, respectively, in comparison to placebo group.[23] Several studies have suggested that diabetic patients using metformin might lower the risk of cancer compared to those using other anti-diabetic drugs.[24,25] However, the results need confirmation in controlled trials.[26]

Metformin has shown a strong antiproliferative effects on colon, pancreatic, breast, ovarian, prostate and lung cancer cells. Preclinical studies have also shown reliable anti-tumoral effects in different animal models. A clinical trial has demonstrated beneficial effect in colon and breast cancers.[27]

The mechanism of this action is not clear. Other anti-diabetic drugs have not shown the same anticancer activities; hence, the anticancer effect of metformin should not be related to anti-diabetic activity of this drug. Metformin possesses antioxidant activity.[28] Antioxidants have been shown to have various beneficial effects such as anticancer,[29,30,31,32] antidiabetes[33] and antiatherosclerosis[34,35] properties. Therefore, some beneficial effects of metformin might be related to its antioxidant activity.

HIV-associated diabetes

The use of some of antiretroviral drugs in HIV-infection has been associated with glucose tolerance, insulin resistance, hyperinsulinemia and type 2 diabetes mellitus. Low HDL, Hypertriglyceridemia and high risk of cardiovascular diseases have been reported in these patients. These metabolic alterations are frequently associated with loss of subcutaneous fat and increased visceral fat.[36,37]

Antiretroviral therapies with protease inhibitors inhibit glucose transporter (GLUT)-4 mediated glucose transport.[38] They are likely to be, in part, responsible for the insulin resistance and body composition changes in HIV-infected patients. Metformin has been shown to reduce visceral adiposity and insulin resistance after 8 weeks of drug therapy at dose of 850 mg, 3 times per day.[39]

Nephrotoxicity prevention

Recent studies have suggested that metformin may have therapeutic or renoprotective effects against nephrotoxic agents.[40,41] It has also been shown to have a good efficacy in diabetic nephropathy.[40,41,42,43,44] Furthermore, it significantly decreases albuminuria in patients with diabetes mellitus.[41,42,43,44] However, the exact mechanism beyond these effects is still unknown. Recent studies have shown that therapeutic effect of metformin is mediated through its action on adenosine monophosphate (AMP)-activated kinase in tissues.[43,44,45,46,47,48] Various studies have shown that metformin is capable of decreasing intracellular reactive oxygen species (ROS).[45,46,47,48,49] It protects tubular injury through regulation of oxidative stress and restoring the biochemical alterations on renal tubules. Metformin may also protect the podocytes in diabetic nephropathy.[47,48,49,50,51]

Various studies have shown that AMPK activation of metformin is secondary to its effect on the mitochondria as the primary target.[52] Recent studies have demonstrated a direct or mediated mitochondrial effect for metformin.[53] When metformin is used alone, its beneficial effect is due to the mild inhibition of the mitochondrial respiration.[54,55]

The effect of mitochondria in programmed cell death is usually associated with the release of apoptotic signaling molecules.[56] Moreover, ROS production by mitochondria may also lead to cell degradation.[57]

Mitochondria represents as one of the major cellular sources of ROS generation,[50] and a great number of tissue pathologies, which induce oxidative stress.[58,59] These findings may show the critical role of mitochondria in these conditions.[58,59]

The nephrotoxicity of aminoglycosides and most of other renotoxic agents has been attributed to ROS.[60] In certain conditions, intracellular ROS may reach a toxic level, resulting in oxidative damage and malfunctioning of the organ.[54]

We conducted a study on male Wistar rats to test the potential properties of metformin in protecting the kidney from gentamicin-induced acute renal failure, and to find out by postponing the treatment with metformin in acute renal failure exerts similar benefits as on gentamicin nephrotoxicity in rats.[61] Metformin not only had preventive effect but also exerted ameliorative activity against gentamicin nephrotoxicity. Hence, it might be beneficial in patients under treatment with this drug.[49]

Metformin has also shown to have beneficial effect on renal function and structure after unilateral ischemia-reperfusion in rats.[62] The authors in this study have concluded that metformin has tissue protection with the activation of endothelial nitric oxide synthase and AMPK.[61]

Various studies have shown that ROS overproduction might be the key starting events, which cause development of complications of diabetes.[63] However, the exact mechanisms that cause hyperglycemia and diabetic nephropathy are not elucidated.[64] It has been shown that nucleic acids can be affected by oxidative stress, thereby modifying the bases in DNA. When DNA is damaged the affected cells start a response such as cell cycle delay, DNA repair or apoptosis induction. ROS generation by oxidative stress causes cell death.[65] Apoptosis is implicated in the pathogenesis of diabetic nephropathy. ROS is an inducer of apoptosis in various cell types including podocytes.[66]

Metformin is able to restore the podocytes in diabetic rats and diabetes-induced podocyte loss in diabetic nephropathy has been attenuated to ROS.[67] Podocyte apoptosis is associated with increased albuminuria. Phosphorylation of AMPK is reduced in the kidney of diabetic rats. Therefore, metformin may exert some of its effects by improving the renal oxidative stress.[67] These findings are in agreement with other studies showing beneficial antioxidant properties of metformin in diabetic rats.[68]

These findings may encourage the clinical use of metformin along with nephrotoxic drugs as well as for prevention of diabetic nephropathy.

Side effects

Metformin has not significant adverse effects; however, it may cause a serious condition called lactic acidosis with the following symptoms: Dizziness, severe drowsiness, muscle pain, tiredness, chills, blue/cold skin, fast/difficult breathing, slow/irregular heartbeat, stomach pain with diarrhea, nausea or vomiting.[1,41,43,69]

Lactic acidosis usually occurs due to drug overdose or in some contraindicated conditions. It is more likely to occur in patients with certain medical conditions, including a serious infection, liver or kidney disease, recent surgery, any conditions that cause a low level of oxygen in the blood or poor circulation (such as recent stroke, congestive heart failure, recent heart attack), heavy alcohol use, dehydration, X-ray or scanning procedures that require an injectable iodinated contrast drug and those older than 80 years.[1,41,43,70]

Nausea, vomiting, stomach upset, diarrhea, weakness, or a metallic taste in the mouth may occur.

Metformin usually does not cause hypoglycemia; however, low blood sugar may occur if this drug is used with other anti-diabetic drugs. Hypoglycemia is more likely to occur with heavy exercise, drinking large amounts of alcohol, or not consuming enough calories from food.

Symptoms of hyperglycemia include polydipsia, polyuria, rapid breathing, flushing, confusion, drowsiness, and fruity breath odor.[1,41,43,71,72]

Serious allergic reaction to this drug is rare; however, this product may contain inactive ingredients, which can cause allergic reactions or other problems. High fever, diarrhea, vomiting, diuretics or excess sweating may cause dehydration and increase the risk of lactic acidosis. Older adults may be at greater risk for side effects such as low blood sugar or lactic acidosis.[1,41,43,62,71]

Gastrointestinal intolerance is one of the most frequently occurred and lactic acidosis is a rare, but causes serious adverse effects.[73,74] Incidence of myocardial infarction (MI) is also an important event but seen less in metformin compared with sulfonylurea agents.[75] Metformin induced lactic acidosis is a rare but important and fatal adverse event.

A population-based study demonstrated that about one-fourth of patients prescribed metformin had contraindications to its use. However, contraindications rarely resulted in discontinuation of metformin usage.[76] These data have been confirmed by several other studies in different countries.[77,78]

Furthermore, in a recent review article, based on 347 observational cohort studies and prospective comparative trials, no evidence indicating metformin to be associated with increased levels of lactate or increased risk of lactic acidosis in comparison to other antihyperglycaemic drugs has been reported.[7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79] It should be noted that in this report, all clinical trials excluded the risk patients. Therefore, the scenario might be rather different, in real population.

In a study sample of 19,691 type 2 diabetes mellitus (DM), patients with established atherothrombosis participating in study, the two-year mortality rate was significantly less in patients treated with metformin compared with the patients not treated with metformin.[80,

Psalm 147:3, And What It Means to All People.

      Good Day Everyone!!  How are you doing today?  Fine, I hope.  I want to inform all of you that Psalms 147:3 is the topic of today.  Psalms 147:3 says; He health the broken in heart, and bindeth up their wounds.  This Bible verse means that God is with all of us.

  He heals our broken hearts, and He bindeth up our wounds.  I want to say that God is my best friend.  God is my Best Friend because He hears my cries, and He smiles at me when I am doing something good.  I know that God rejoices when we do things that pleases Him.

Further, I want to inform all of you that God helped me graduate from college on two occasions.  I want to say that God is responsible for helping me with my bad attitude.  I know this because; His Spirit is inside of me. According to John 14:26, it states that He will give you an Advocate, which is the Holy Spirit to teach you, and put things into your remembrance.

      The Lord is still inside of us.  He is doing for all of us, more than we are doing for ourselves.  I want to inform all of you that everything that is inside of the Holy Bible is the truth.  At least, I can say that it reminds me of the Footprints inside of the Sand. God is really with us at all times. 

I know for me personally, I remember when I used to use vulgarity all of the time.  Right Now, I ask God to remove the bad thoughts that I have inside of my heart.  I know that we have to remember who is in charge right now.  It is not me; personally, it is God.  God knew all of us before we were born.  According to Jeremiah 1:5 states that: Before you were born, I knew you, before you were born, I sanctified you, and ordained you as a prophet to the Nations.

   God understands our heart, mind, soul, and emotions.  I have been writing essays for the past 30 years now.  I have been keeping a journal since I was in the 7^th grade.  I have been writing down my personal feelings inside of a tablet for many years now.  The teachers used to remind all of us as students to write down our personal feelings.  This is what I have been doing for 45 years now.

        I write down all of my feelings.  I share my journal with my therapist.  I have been sharing with him what the voices have been saying to me.  Yes, I suffer from Schizoid Affective Disorder right now.  I have been suffering from a mental illness for the past 25 years now.

  I know that God is with me every single day of the week.  My therapist does not want me to write down what the voices are saying to me.  It is like; living inside of the problem all over again.  I am trying to cope with something that I have had for the past 25 years now.  I am a very happy person right now. I have been keeping my emotions in check for the past 13 years now.

      Finally, I want to inform all of you that I love all of you very much.  I have been clean and sober for the past 32 years now.  I have not smoked marijuana since Wednesday May 2, 1990.  I have not consumed any alcohol since May 2, 1990.  I am very happy to be clean and sober right now. 

In Conclusion, I want to say that I do not hang around my friends, who drink alcohol and smoke marijuana because I can end up getting caught up all over again.  I do not smoke cigarettes.  I have not smoked a cigarette since January 21, 1990.  This is the reason why I know that God is with me.  I am very happy to become a Child of The Most High God.  I am happy, joyous, and free.

Psalm 147:3, And What It Means to All People.

      Good Day Everyone!!  How are you doing today?  Fine, I hope.  I want to inform all of you that Psalms 147:3 is the topic of today.  Psalms 147:3 says; He health the broken in heart, and bindeth up their wounds.  This Bible verse means that God is with all of us.

  He heals our broken hearts, and He bindeth up our wounds.  I want to say that God is my best friend.  God is my Best Friend because He hears my cries, and He smiles at me when I am doing something good.  I know that God rejoices when we do things that pleases Him.

Further, I want to inform all of you that God helped me graduate from college on two occasions.  I want to say that God is responsible for helping me with my bad attitude.  I know this because; His Spirit is inside of me. According to John 14:26, it states that He will give you an Advocate, which is the Holy Spirit to teach you, and put things into your remembrance.

      The Lord is still inside of us.  He is doing for all of us, more than we are doing for ourselves.  I want to inform all of you that everything that is inside of the Holy Bible is the truth.  At least, I can say that it reminds me of the Footprints inside of the Sand. God is really with us at all times. 

I know for me personally, I remember when I used to use vulgarity all of the time.  Right Now, I ask God to remove the bad thoughts that I have inside of my heart.  I know that we have to remember who is in charge right now.  It is not me; personally, it is God.  God knew all of us before we were born.  According to Jeremiah 1:5 states that: Before you were born, I knew you, before you were born, I sanctified you, and ordained you as a prophet to the Nations.

   God understands our heart, mind, soul, and emotions.  I have been writing essays for the past 30 years now.  I have been keeping a journal since I was in the 7^th grade.  I have been writing down my personal feelings inside of a tablet for many years now.  The teachers used to remind all of us as students to write down our personal feelings.  This is what I have been doing for 45 years now.

        I write down all of my feelings.  I share my journal with my therapist.  I have been sharing with him what the voices have been saying to me.  Yes, I suffer from Schizoid Affective Disorder right now.  I have been suffering from a mental illness for the past 27 years now.

  I know that God is with me every single day of the week.  My therapist does not want me to write down what the voices are saying to me.  It is like; living inside of the problem all over again.  I am trying to cope with something that I have had for the past 27 years now.  I am a very happy person right now. I have been keeping my emotions in check for the past 15 years now.

      Finally, I want to inform all of you that I love all of you very much.  I have been clean and sober for the past 33 years now.  I have not smoked marijuana since Wednesday May 2, 1990.  I have not consumed any alcohol since May 2, 1990.  I am very happy to be clean and sober right now. 

In Conclusion, I want to say that I do not hang around my friends, who drink alcohol and smoke marijuana because I can end up getting caught up all over again.  I do not smoke cigarettes.  I have not smoked a cigarette since January 21, 1990.  This is the reason why I know that God is with me.  I am very happy to become a Child of The Most High God.  I am happy, joyous, and free.

I want to start things off by saying that I have full blown Diabetes.  I know that Jesus Christ will help me to cope with the disease.  I have to really watch what I eat and drink on a daily basis.  It really hurts me so much �. I also know that I have Peripheral Artery Disease.  I  suffer from Grandmal Seizures, Gastric Ulcers, and Schizoid Affective Disorder.  I suffer from other physical problems that I am taking medication at the moment.

I know that I have to change everything in my life right now.  I have to allow God to help me out.  I have to go to the hospital on a regular basis.  I have to check my blood sugar levels on a daily basis.  I have to watch my stress levels on a daily basis.  I have to take my Medfordman on a daily basis before eating breakfast. I have to attend church on a regular basis.  I have to keep my emotions in check for the rest of my life.  As long as I am living with a terminal disease, I have to become humble and meek because I am not trying to leave here foolishly.  I also have to change my environment.  My family members use vulgarity towards me because I am only telling them that marijuana and other drugs are inside of my building.  Lord Jesus, I am asking you to please lead me and guide me along in this process.

Next, I have to consult with an endocrinologist and a podiatrist on a regular basis.  I have to maintain a personal relationship with God.  I have to lose weight really bad.  I also have to take my other medications on a daily basis as well.  I have to get a grip of this problem in order for me to maintain my sanity.  This is not a very easy topic to talk about because I tend to blame my own self for this problem.  I know that I have placed this problem inside of God’s Hands right now.  I have been overweight for a very long time right now.  I want to inform all of you that I am going to continue to share my personal feelings about Diabetes.  Perhaps, I can become an ambassador for this disease.

Finally, I have to go to the library on a regular basis in order to get out of my apartment building each day.  I also have to stop using vulgarity and have a positive attitude about life in general.  I have to see my therapist and psychiatrist on a regular basis.  have never been through anything like this before.  This is the first time for everything.  I realize that I have been anemic for 25 years now.  I have noticed when it gets cold outside, I tend to shiver really bad.  Therefore, cool weather and environments are not my best friend.  I tend to get cold while I am at home with the A/C is on.  I do not have enough red blood inside of my body.  I will admit that I have been taking over 25 medications per day for at least 27 years now.  Sometimes taking too much medication can take a complete toll on your body.  I have to question all of my current physicians right now because I really need to know how I ended up with Diabetes at an early age.  I know that I had taken Depakote for a mood stabilizer and seizure medication in the past.  I know that I had gained 85 pounds in one year in the year 1998.  There are times when doctors prescribe too much medication.  Especially when you are a Psychiatric Patient just to stabilize you within a short period of time.